Understanding Oxygen Therapy

Oxygen therapy is a treatment that provides you with extra oxygen, a gas that your body needs to work well. Normally, your lungs absorb oxygen from the air. However, some diseases and conditions can prevent you from getting enough oxygen.

Oxygen therapy helps you function better and be more active. Concentrated oxygen is supplied by an oxygen concentrator. It flows through a tube and is delivered to your lungs in one of the following ways:

  1. Through a nasal cannula, which consists of two small plastic tubes, or prongs, that are placed in both nostrils.
  2. Through a face mask, which fits over your nose and mouth.
The amount of energy production in the human body is mostly from the chemical regeneration of adenosine triphosphate (ATP) according to the needs of the body and is primarily dependent on oxygen first, and nutrients second. The production of energy from the intake of food rests on oxygen delivery from blood to tissues, and then into the cell. Oxygen deficiency can be defined as the combined individual effect of critically reduced oxygen transport to the tissues, critically reduced oxygen utilization of the tissues, and critically increased oxygen requirements of the tissues in the wake of illness and disorder. Disease and disorder rotates around oxygen first, nutrients second. This is a pivotal concept of all therapeutics.

The quest for oxygen therapies is based on research into individual diseases of old age, and has delivered unequivocal clinical breakthroughs. Attempts to treat most age-related diseases using high dose vitamins, minerals, herbs and antioxidant supplements have been very helpful, yet in some cases equally disappointing, despite the clear benefits of a healthy diet. Marginal results of natural therapeutics begins and ends in a patient who is not getting enough oxygen to the tissues. This core fundamental stares us in our face, and is the failure of our therapeutic and medical institutions and schools to recognize this.

The double-agent theory of Lane is a new, unifying synthesis that draws on flaws in leading theories of biological aging, leading to a unifying concept: a tradeoff between oxidative stress as a critical redox signal that marshals genetic defenses against physiological stress (such as toxicity and infection) and oxidative stress (free radicals) as a cause of and age-related disease. Thus aging is caused by free radicals, and its rate and speed modulated by genetics. Epigenetics describes the study of dynamic alterations in the transcriptional potentials of a cell, alterations which may or may not be heritable, which can be triggered by vaccines and chemical pollutants, but the end result is still free radical damage.

The stress responses and aging have been linked by redox-sensitive transcription factors, such as NFkappaB. Aging, bottom line, is a function of rising intracellular oxidative stress caused by free radicals, rather than chronological time, but this relationship is obscured because free-radical leakage from mitochondria also tends to rise with age.

Mitochondrial leakage and reduced energy production produces a genetic response which mirrors that following infection, but because mitochondrial leakage is continuous and the shift in gene expression is persistent, leads to the chronic inflammation characteristic of old age.

Age-related diseases are thus the price we pay for loss of redox control of stress-gene expression. Because the selective pressure favoring the stress response in youth is stronger than degenerative diseases after reproductive (hormonal) decline, we may be homeostatically resistant to antioxidant supplements that 'swamp' the redox switches that are normally part of our physiology. Taking antioxidant supplements while ignoring oxygen requirements is aging on the installment plan.

Furthermore, because genetic selection takes place predominantly in the reductive homeostatic environment of youth, genes associated with age-related diseases are not inherently damned, they do not inevitably express a total negative effect over time, but are simply less effective in the oxidizing conditions of old age. The quest for therapies based on molecular genetics drives pharmaceutical research into individual diseases of old age, but has failed to deliver an unequivocal clinical breakthrough. Gene therapies for age-related diseases are unlikely to succeed unless oxidative stress can be controlled physiologically, thereby altering the activity and function of potentially hundreds of genes.

The diseases of old age are the result for the way that we are set up to handle physiological stresses, such as infections, in our youth. Infections and age-related diseases are linked by oxidative stress - an imbalance in the production and elimination of oxygen and nitrogen free radicals, and other related species - but the outcomes are opposed: resistance to stress in youth and vulnerability to disease in old age. The failure to subdue the rising oxidative cellular stress is a primary cause of aging which rotates around oxygen.